Osilodrostat (LCI699) Handle

Osilodrostat (LCI699) HandleLCI699(Osilodrostat) is a potent inhibitor of 11? hydroxylase, an enzyme catalyzing the final step of cortisol synthesis.

antagonizing the action of acetylcholine by inhibiting neuromuscular transmission

synthetic sulfanilamide derivative

Its interaction with quinolone antibacterial agents can induce functional blockade of the

Sodium cholate (NaCh) is the sodium salt of the naturally occurring cholic acid

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay

7 nAChRs with IC50 of 49 nM and 122 nM

PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0

weakly inhibits KDR and Src

anti-cancer

LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1

GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM in cell-free assays

a semi-synthetic first-generation cephalosporin with antibacterial activity