Pexidartinib (PLX3397) Binding

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Description

Pexidartinib (PLX3397) BindingPexidartinib (PLX3397) is an oral, potent mutil targeted receptor tyrosine kinase inhibitor of CSF 1R, Kit, and Flt3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Phase 3.

anti-allergy

Epigallocatechin gallate (EGCG)

5mm Transwell-COL with Collagen-Coated 3

PD 151746 is a selective

Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA)

inhibitor with IC50 of about 5

Chlortetracycline is a tetracycline antibiotic and commonly used to treat conjunctivitis in cats

1 adrenergic receptor blocker

Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry

exhibiting a 35-fold selectivity versus EZH1 and >4

PRT-060318 (PRT318) is a novel selective inhibitor of the Syk tyrosine kinase with an IC50 of 4 nM

with Ki of 15 nM

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