LXR-623 (WAY-252623) 383

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Description

LXR-623 (WAY-252623) 383LXR 623 is a novel liver X receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR ? and LXR ?, respectively. It is orally bioavailable and readily passes the blood brain barrier.

SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays

Oxybuprocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions

with high affinity

Folic acid

>100-fold more selective for IGF-1R/InsR than Akt1/2

Tubulation has a 7mm O

4 nM in a cell-free assay and demonstrates >1

U73122 is a potent phospholipase C (PLC) inhibitor

M for CBP and EP300 respectively in TR-FRET assay

It functions as a NF-

used to treat overactive bladder syndrome

such as apples

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