LY3009120 Extractor

LY3009120 ExtractorLY03009120 is a potent pan Raf inhibitor with IC50 of 44 nM, 31 47 nM, and 42 nM for A raf, B Raf, and C Raf in A375 cells, respectively. Phase 1.

Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM

It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR

it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex

modifications saved to the Audit Trail file

Gilteritinib(ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0

is mainly used for treating purulent skin infections

LY2409881 is a potent and selective IKK2 inhibitor with IC50 of 30 nM

modulates ion homeostasis and metabolism

(IC50 for canine influenza virus ranges from 0

Licochalcone A is an estrogenic flavanoid extracted from licorice root

Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent

6 nM in a cell-free assay